Organo-Metalloid Compounds
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- (115)
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Filtered Search Results
Medchemexpress LLC PS-1145 | 431898-65-6 | 99.7% | 322.75 | 1 MG
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PS-1145 | 431898-65-6 | 99.7% | 322.75 | 1 MG
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(C)c1cncs1 | 5g | 256640244](https://assets.fishersci.com/TFS-Assets/CCG/product-images/VN00128114-256640244.PNG-250.jpg)
eMolecules 79265-36-4 | 5-TRIMETHYLSILANYLTHIAZOLE | AstaTech | MFCD00191506 | 157.310 | C6H11NSSi | 97.000 | C[Si](C)(C)c1cncs1 | 5g | 256640244
5-TRIMETHYLSILANYLTHIAZOLE | AstaTech | 79265-36-4 | MFCD00191506 | 157.310 | C6H11NSSi | 97.000 | C[Si](C)(C)c1cncs1 | 5g | 256640244
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Medchemexpress LLC AK-778-XXMU | 1227045-76-2 | 99.9% | C22H17ClN2O3 | 50 MG
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AK-778-XXMU is a potent DNA binding inhibitor 2 (ID2) antagonist with a KD of 129 nM, used for the study of glioma. It inhibits the ID2-KDR signaling axis, leading to the downregulation of downstream angiogenic factors and invasion-related proteins, and the upregulation of the tumor suppressor factor PTEN. This compound demonstrates significant cancer-suppressing potency by inhibiting cell migration and invasion of glioma cell lines and inducing apoptosis.
- Potent ID2 antagonist with a KD of 129 nM
- Inhibits cell migration and invasion of glioma cell lines
- Induces apoptosis
- Inhibits ID2-KDR signaling axis
- Downregulates angiogenic factors (VEGFA) and invasion-related proteins (MMP2/9)
- Upregulates tumor suppressor factor (PTEN)
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Medchemexpress LLC PS-1145 | 431898-65-6 | 99.67% | 322.75 | 25 MG
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PS-1145 is an IκB kinase (IKK) inhibitor with an IC50 of 88 nM.
- Blocks TNFα-induced NF-κB activation in a dose- and time-dependent manner in MM cells through inhibition of IκBα phosphorylation.
- Dexamethasone enhances the blockade of NF-κB activation by the product.
- Blocks the protective effect of IL-6 against Dexamethasone-induced apoptosis.
- Inhibits TNFα-induced intracellular adhesion molecule (ICAM)-1 expression.
- Inhibits both IL-6 secretion from bone marrow stromal cells (BMSCs) triggered by MM cell adhesion and proliferation of MM cells adherent to BMSCs.
- Administration results in a significant decrease in serum levels of three cytokines.
- Blocks hypothalamic inflammation induced by IL-4.
- Decreases IL-1β mRNA content.
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Medchemexpress LLC AK-778-XXMU | 1227045-76-2 | 99.9% | C22H17ClN2O3 | 25 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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AK-778-XXMU is a potent DNA binding inhibitor 2 (ID2) antagonist with a KD of 129 nM. It inhibits the ID2-KDR signaling axis, leading to the down-regulation of downstream angiogenic factors (VEGFA) and invasion-related proteins (MMP2/9), while up-regulating the tumor suppressor factor (PTEN). It can inhibit cell migration and invasion of glioma cell lines, induce apoptosis, and demonstrates significant cancer-suppressing potency. This compound is used for the study of glioma.
- Potent DNA binding inhibitor 2 (ID2) antagonist
- Inhibits cell migration and invasion of glioma cell lines
- Induces apoptosis
- Demonstrates significant cancer-suppressing potency
- Inhibits ID2-KDR signaling axis
- Down-regulates angiogenic factors (VEGFA) and invasion-related proteins (MMP2/9)
- Up-regulates tumor suppressor factor (PTEN)
- Suitable for the study of glioma
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eMolecules 1503378-02-6 | ChemScene | 7-Methoxy-23-dihydrobenzofuran-3-carboxylic acid | 100mg | 712840997 | CS-0438340 | MFCD26129953 | 194.186 | C10H10O4
Ambeed | 4-Bromo-2-(26-dioxopiperidin-3-yl)isoindoline-13-dione | 250mg | 633418021 | A1215363 | 2093536-12-8 | 337.129 | C13H9BrN2O4
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(OC)c1ccccc1 | 10g | 525102076](https://assets.fishersci.com/TFS-Assets/CCG/product-images/NC2039302.JPG-250.jpg)
eMolecules 3027-21-2 | Dimethoxy(methyl)(phenyl)silane | Ambeed | MFCD00008343 | 182.294 | C9H14O2Si | 98 | CO[Si](C)(OC)c1ccccc1 | 10g | 525102076
Ambeed | (S)-2-((2R3R)-3-((S)-1-((3R4S5S)-4-((S)-N3-Dimethyl-2-((S)-3-methyl-2-(methylamino)butanamido)butanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanamido)-3-phenylpropanoic acid | 2mg | 491171472 | A309085 | 745017-94-1 | MFCD25976742 | 731.976 | C39H65N5O8
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![eMolecules 164526-16-3 | (7-Amino-2,3-dihydrobenzo[1,4]dioxin-6-yl) (2-chlorophenyl)methanone | Oakwood Chemical | MFCD00561832 | 289.720 | C15H12ClNO3 | 95.000 | Nc1cc2OCCOc2cc1C(=O)c1ccccc1Cl | 100mg | 537683527](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502149491.JPG-250.jpg)
eMolecules 164526-16-3 | (7-Amino-2,3-dihydrobenzo[1,4]dioxin-6-yl) (2-chlorophenyl)methanone | Oakwood Chemical | MFCD00561832 | 289.720 | C15H12ClNO3 | 95.000 | Nc1cc2OCCOc2cc1C(=O)c1ccccc1Cl | 100mg | 537683527
(7-Amino-2,3-dihydrobenzo[1,4]dioxin-6-yl) (2-chlorophenyl)methanone | Oakwood Chemical | 164526-16-3 | MFCD00561832 | 289.720 | C15H12ClNO3 | 95.000 | Nc1cc2OCCOc2cc1C(=O)c1ccccc1Cl | 100mg | 537683527
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Aobchem 2-((2-Bromophenoxy)methyl)-1 3-dichlorobenzene | ≥95% | CAS 1039821-17-4 | C13H9BrCl2O | 500mg
2-((2-Bromophenoxy)methyl)-1 3-dichlorobenzene | ≥95% | CAS 1039821-17-4 | C13H9BrCl2O | 500mg
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Aobchem 2-(4-Bromophenoxy)-N N-diethylethanamine | ≥95% | CAS 1823-62-7 | C12H18BrNO | 250mg
2-(4-Bromophenoxy)-N N-diethylethanamine | ≥95% | CAS 1823-62-7 | C12H18BrNO | 250mg
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Aobchem AOBCHEM
5000960708 TRIMETHYL 4-PROPYLPHENYL SILAN
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Aobchem AOBCHEM
5000961119 TRIMETHYL 4-PROPYLPHENYL SILAN
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Aobchem AOBCHEM
5000966112 METHYL -HYDROXY- 2 4-TRIMETH
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